1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU)
RELATED: DBN, t-BuOK
Most Common Uses
- strong, sterically-hindered, non-nucleophilic base used in
- E2 reactions to preferentially form the less-substituted (“Hofmann” or “anti-Zaitsev”) alkene
E2 Elimination
FGT: alkyl halide ➛ alkene
TYPE: elimination
REGIOCHEM: Hofmann
STEREOCHEM: anti-elimination
